SPE Retention: Reversed-Phase and Mixed-Mode

Learning Goals:
• Understand what solid-phase extraction (SPE) is
• Learn how reversed-phase (RP) SPE retention mechanisms work
• Be introduced to silica and polymeric base sorbent particles and know the differences
• Learn how mixed-mode ion exchange (MM) SPE retention mechanisms work
• Be able to answer “why would you choose RP-SPE over MM-SPE?” and vice versa

Watch the tutorial video below and then attempt the tutorial quiz.